INFLAMMATION AND SPORT

High-performance sports and resistance training induce an acute inflammatory state that is essential for musculoskeletal tissue adaptation and remodeling; however, its efficient resolution is crucial to prevent progression to persistent inflammation, chronic fatigue, overuse injuries, and muscle loss.

Sports injuries associated with inflammation and pain:

• Muscle damage from intense exercise
• Musculoskeletal injuries
• Overload or stress fractures
• Concussion and mild brain injury (TBI)
• Disorders linked to fear and anxiety

Athletes often opt for conventional treatments for inflammation and pain, but these focus on inhibiting, suppressing, or blocking the natural acute inflammatory response, which can delay or hinder its resolution and cause side effects. Unlike these, SPMs do not block inflammation; instead, they support the body's ability to resolve this process naturally without suppressing the immune response.

In this context, supplementation with specialized pro-resolving mediators (SPMs) has demonstrated potential to modulate inflammation, allowing for faster and optimal functional recovery without interfering with exercise-induced adaptations.