Omega-3s EPA and DHA are the substrates from which our body biosynthesizes SPMs. While EPA and DHA are essential fatty acids and form a structural part of our cells, SPMs are the derivatives that act directly to resolve inflammation, with measurable and targeted effects.

Inflammation is a natural and protective response of our immune system against tissue damage, cellular injuries, pathogens or irritants, which helps eliminate invading organisms and repair damaged tissues.

The resolution of inflammation is a very important part of the inflammatory response. It is an active process, orchestrated by the PMS, that signals the end of the inflammatory reaction, allowing the body to return to homeostasis, or balance. Excessive and prolonged inflammation can occur when the response is not "turned off," which, for athletes, can translate into a risk of injury and limited performance.

SPMs—known as Specialized Pro-resolving Mediators—promote the resolution of inflammation. They act as "stop" signals in the inflammatory response, counteract pro-inflammatory mediators, reduce pain, and promote the phagocytosis of pathogens and cellular debris generated during the process, clearing the environment and promoting tissue regeneration.

Traditional anti-inflammatories reduce inflammation by blocking the natural inflammatory response, which can lead to adverse effects if taken continuously and can compromise the immune system, while SPMs support the body's ability to resolve inflammation naturally.

More than 600 peer-reviewed publications support the role of SPMs in resolving inflammation, including human clinical trials. Studies have been conducted by institutions such as Harvard Medical School, Brigham and Women's Hospital, and other prestigious universities. Sports ProResolve® is formulated with Lipinova® SPMs , a unique, patented ingredient that has demonstrated safety and efficacy results in several clinical studies, some of which have already been published.

In general, yes. Sports ProResolve® is compatible with most protein supplements, vitamins, and recovery products. However, it is always recommended to consult a healthcare professional.

Yes. SPMs have been evaluated in physically active individuals and athletes, demonstrating improvements in recovery, post-exercise soreness, and fatigue. The Sports ProResolve® formulation is specifically designed for this profile.

In addition to users reporting feeling better after taking SPMs, advanced lipidomics techniques can quantify SPM levels in the blood and their relationship with biomarkers of inflammation and resolution. Clinical studies have correlated modulation of SPM levels with improved functional outcomes.

It doesn't replace proper preparation or rest, but by speeding up the resolution of inflammation and optimizing recovery, it can help reduce the risk of overuse injuries or poor recovery.

The recommended dosage is based on the concentration of bioactive SPMs and available clinical evidence. The scientific evidence is based on the Lipinova® ingredient, so the recommended dose is 2 capsules daily, and up to 4 capsules daily during times of high physical stress.